Veterinary Medicines Directorate
Companies are encouraged to report supply problems to the Veterinary Medicines Directorate.
Where a supply problem exists and there is no alternative product, vets may prescribe using the cascade. Vets are reminded that it is their responsibility to apply use of the Cascade appropriately based on clinical need
More information can be found on The Cascade: Prescribing unauthorised medicines page.
For non-UK products vets must apply for a certificate to import a Veterinary Medicine into the UK.
For information on manufacturers of extemporaneous products, please read the ManSA Register
Supply problems exist with the following products
Vaccine for immunisation against ringworm
The VMD is aware of a supply problem for Bovilis Ringvac (Intervet UK Ltd), indicated for the active immunisation of cattle to reduce clinical signs of ringworm caused by Trichophyton verrucosum.
Due to the clinical need for a vaccine of this indication in the UK, the VMD has approved Trichoben for import. Trichoben is authorised in both the Czech Republic and Netherlands as per the following
|Country of Origin:||Czech Republic|
|Country of Origin:||Netherlands|
|MA Number:||REG NL 121040|
|Distributor Contact Details||Animal Health Distributors. email: SDMHOUSE@blueyonder.co.uk or email@example.com telephone: 07804 601851 or +353 87 230 2034|
To address the supply problem, veterinary surgeons may consider use of the above products under the cascade once the necessary import certificate has been obtained. If veterinary surgeons are aware of any other alternative vaccines, they can submit an SIC application for these vaccines. Each application will be assessed on its individual merits.
In advance of applying for SICs for any product it is recommended that the supplier is contacted to ensure that sufficient stock is available to meet your needs.
More information can be found on the VMDs Special Import Scheme guidance page.
Products containing acepromazine for anaesthetic premedication, tranquilisation and sedation in horses
Following the granting of a marketing authorisation the VMD have been informed that there is availability of a 10mg/ml acepromazine solution for injection:
- AceSedate 10mg/ml solution for injection for horses Vm: 25296/4008
Therefore the VMD will no longer issue import certificates for alternative acepromazine products, including:
- Calmivet solution for injection (5mg/ml), licensed in France
- Vetranquiol 1% solution for injection (10mg/ml), licensed in Germany and Netherlands
This will take effect immediately.
Existing certificates will remain valid until their date of expiry, however veterinary surgeons are reminded to apply the Cascade responsibly and use UK authorised product where available.
2mg/ml presentations are also available. Information on authorised acepromazine-containing products is available on the VMDs Product Information Database.
Vaccines for immunisation against Leptospira hardjo and Leptospira borgpetersenii
The VMD have been informed that there is now supply of two UK authorised Leptospirosis vaccines indicated for cattle: Leptavoid-H Suspension for Injection for Cattle Vm: 01708/4568 and Spirovac Vm: 42058/4134.
The VMD will no longer accept applications to import alternative products BioBos L injection for cattle, licensed in Czech Republic or Spirovac, licensed in the USA.
Local anaesthetic products containing procaine hydrochloride
The VMD is aware of UK availability issues with some veterinary medicinal local anaesthetic products containing procaine hydrochloride.
Information on authorised procaine hydrochloride-containing products and other local anaesthetics are available on the VMDs Product Information Database.
Suppliers advise the UK authorised Pronestesic 40 mg/ml / 0.036 mg/ml Solution for Injection for Horses, Cattle, Pigs and Sheep (Vm 11557/4002) is currently available to meet present demand.
Contact details for the named distributor are: DUGV UK Tel 07540 552976
Viper Venom Antiserum for veterinary use (adder bite antivenom)
There is no viper venom antiserum licensed in the UK for the treatment of adder bites in animals.
VMD accept applications to import European Viper Antiserum from Biomed (Poland) and Institute of Immunology, Zagreb (Croatia).
Before submitting an application contact the relevant manufacturer to ensure they are able to supply the quantity of product you wish to import.
Contact details of the approved manufacturers
Wytwornia Surowic i szczepionek BIOMED Ltd
Ul. Chelmska 30/34
Phone. 022 841 4071
Institute of Immunology
10000 Zagreb, Croatia
Phone +385 1 46 84 500
In urgent cases the antivenom may be supplied, purchased and used prior to the special treatment certificate being obtained from the VMD. This is a special dispensation made for this clinical condition only.